https://journals.tultech.eu/index.php/ijitis <p>The <strong>International Journal of Innovative Technology and Interdisciplinary Sciences (IJITIS) (ISSN 2613-7305)</strong> is a reputable open-access, quarterly multidisciplinary journal that serves as a platform for the publication of reviews, regular research papers, short communications, and special issues on specific subjects, all presented in the English language. With a focus on fostering academic exchange and disseminating original research, IJITIS showcases the latest advancements and achievements in scientific research from Estonia and beyond to a global audience. Our journal welcomes original and innovative contributions across various fields of technology, innovation in the sciences, and interdisciplinary studies. We encourage submissions that provide valuable insights through analytical, computational modeling, and experimental research results. IJITIS is guided by an esteemed international board of editors comprised of distinguished local and foreign scientists and researchers. Notably, we actively seek manuscripts that introduce new research proposals and ideas, and we offer the option for authors to submit supplementary material such as electronic files or software to enhance the transparency and reproducibility of their work.</p> TULTECH en-US International Journal of Innovative Technology and Interdisciplinary Sciences 2613-7305 https://journals.tultech.eu/index.php/ijitis/article/view/206 <div class="page" title="Page 1"> <div class="layoutArea"> <div class="column"> <p>As the incidence of neurodegenerative diseases continues to increase, it is essential to evaluate the causal factors that lead to neurodegeneration and resultant memory loss. In this study, Caenorhabditis elegans were used as a model organism to explore the effects of developmental stress on learning and short-term memory. Half of the population were placed into elevated temperatures, to invoke heat stress, while the other half was kept at their optimal functioning temperature of 22°C. The worms were then taught a simple chemosensory learning task. Results show that 25°C produced a small reduction in learning, while 28°C produced a substantial reduction. In a follow-up study, C. elegans were exposed to 28°C at different life stages Day 0 (embryo), Day 1, Day 2, and Day 3 stress each reduced learning when compared to controls, with the greatest deficit being stress experienced during Day 2. Insights into neurodevelopmental time periods of vulnerability to stress and the potential mechanisms affected by early-life stress can help in the prevention of neurodegenerative diseases and their associated cognitive decline.</p> </div> </div> </div> Patrick Nebl Samantha Michniak Amy Hebert Copyright (c) 2025 Patrick Nebl, Samantha Michniak, Amy Hebert https://creativecommons.org/licenses/by/4.0 2025-04-19 2025-04-19 8 2 313 323 10.15157/IJITIS.2025.8.2.313-323